On March 27 from 9:00 A.M.–3:00 P.M. ET, the U.S. Food and Drug Administration (FDA) will hold a hybrid public meeting to discuss the evolving landscape of dietary supplement ingredients and how recent scientific and technological advances are shaping the sector.

The event will explore:

• The scope of the phrase “dietary substance for use by man to supplement the diet by increasing the total dietary intake” as used in the Dietary Supplement Health and Education Act of 1994 (DSHEA)
• New methodologies to produce existing dietary ingredients (e.g., precision fermentation, cell culture technology, and recombinant processes) and whether they fall under the DSHEA framework
• Specific ingredient types, including proteins, enzymes, and microbials, within the context of DSHEA.

The meeting will include an opportunity for interested parties to provide oral comments for FDA’s consideration. FDA will review input received at the public meeting and submitted to www.regulations.gov (docket number FDA-2026-N-2047) to determine next steps. Comments must be submitted on or before April 27, 2026.

Registration for in-person and virtual attendance can be accessed here.