Food Safety
search
Ask Food Safety AI
cart
facebook twitter linkedin instagram youtube
  • Sign In
  • Create Account
  • Sign Out
  • My Account
Food Safety
  • NEWS
    • Latest News
    • Sponsor Insights
    • Sponsored White Papers
  • PRODUCTS
  • TOPICS
    • Contamination Control
    • Food Types
    • Management
    • Process Control
    • Regulatory
    • Sanitation
    • Supply Chain
    • Testing and Analysis
  • PODCAST
  • EXCLUSIVES
    • Food Safety Five Newsreel
    • eBooks
    • FSM Distinguished Service Award
    • Interactive Product Spotlights
    • Videos
  • BUYER'S GUIDE
  • MORE
    • NEWSLETTERS >
      • Archive Issues
      • Subscribe to eNews
    • Store
    • ASK FSM AI
  • WEBINARS
  • FOOD SAFETY SUMMIT
  • EMAG
    • eMagazine
    • Archive Issues
    • Editorial Advisory Board
    • Contact
    • Advertise
  • SIGN UP!
ProductsTesting & AnalysisChemical Testing & AnalysisMethods

LGC Standards Offers New PFAS Reference Materials for EPA Method 1633

By Food Safety Magazine Editorial Team
LCG standards logo
Image credit: LCG Standards
September 30, 2025

LGC Standards has expanded its Dr. Ehrenstorfer PFAS portfolio with new 13C-labeled reference materials developed for U.S Environmental Protection Agency (EPA) Method 1633. The release includes two ready-to-use isotope-labeled internal standard mixtures—one with 24 analytes and another with seven analytes—as well as a broad selection of single compound solutions. These materials are intended to support calibration and improve data quality across water, solid, and tissue matrices.

Per- and polyfluoroalkyl substances (PFAS), also known as “forever chemicals,” are a group of over 1,200 synthetic chemicals used widely for industrial purposes and in consumer goods since the 1940s. Known for their persistence in the environment and resistance to degradation, PFAS accumulate in soil, water, animals, and humans, and have long biological half-lives. Exposure has been associated with developmental effects, immune system disruption, and certain cancers. Regulatory limits for PFAS are increasingly stringent, often set at parts-per-trillion levels, making accurate and traceable testing essential for environmental and public health protection.

EPA Method 1633A, issued in December 2024, is the only PFAS chemical testing method validated across multiple laboratories for a wide range of matrices, including wastewater, surface water, groundwater, landfill leachate, soil, sediment, biosolids, and fish or shellfish tissue.

The new LGC Standards mixtures include:

  • EPA Method 1633 EIS Labeled PFAS Mixture (24 analytes; 0.25–5 micrograms per milliliter [µg/mL], 1 mL; Part No. DRE-A50000792MW), added before extraction to monitor sample preparation recovery.
  • EPA Method 1633 NIS Labeled PFAS Mixture (seven analytes; 0.25–1 µg/mL, 1 mL; Part No. DRE-A50000794MW), added before injection to correct for instrument response.

Both mixtures are formulated for stability and routine use, helping laboratories reduce calibration frequency, account for matrix effects and instrument variability, and avoid the need to prepare in-house blends. They align with EPA Method 1633A’s prescribed values to support reliable quantitation and regulatory compliance.


 LGC Standards: www.lgcstandards.com.

Looking for quick answers on food safety topics?
Try Ask FSM, our new smart AI search tool.
Ask FSM →

KEYWORDS: LGC Standards PFAS

Share This Story

Fsm purple logo 200x200

The Food Safety Magazine editorial team comprises Bailee Henderson, Digital Editor ✉ and Adrienne Blume, M.A., Editorial Director.

Recommended Content

JOIN TODAY
to unlock your recommendations.

Already have an account? Sign In

  • people holding baby chicks

    Serovar Differences Matter: Utility of Deep Serotyping in Broiler Production and Processing

    This article discusses the significance of Salmonella in...
    Contamination Control
    By: Nikki Shariat Ph.D.
  • woman washing hands

    Building a Culture of Hygiene in the Food Processing Plant

    Everyone entering a food processing facility needs to...
    Personal Hygiene/Handwashing
    By: Richard F. Stier, M.S.
  • graphical representation of earth over dirt

    Climate Change and Emerging Risks to Food Safety: Building Climate Resilience

    This article examines the multifaceted threats to food...
    Contamination Control
    By: Maria Cristina Tirado Ph.D., D.V.M. and Shamini Albert Raj M.A.
Manage My Account
  • eMagazine Subscription
  • Subscribe to Newsletters
  • Manage My Preferences
  • Website Registration
  • Subscription Customer Service

More Videos

Sponsored Content

Sponsored Content is a special paid section where industry companies provide high quality, objective, non-commercial content around topics of interest to the Food Safety Magazine audience. All Sponsored Content is supplied by the advertising company and any opinions expressed in this article are those of the author and not necessarily reflect the views of Food Safety Magazine or its parent company, BNP Media. Interested in participating in our Sponsored Content section? Contact your local rep!

close
  • Darkling Beetle
    Sponsored byElanco Animal Health

    Integrated Pest Management: Protecting Poultry Operations as Seasons Change

  • NEVIFIT 3 Compartment BPA-FREE
    Sponsored byCorbion

    The Risks of Ready-to-Eat: Five Ways to Protect Today's Prepared Meals

  • a group of workers in a food production facility
    Sponsored bySkillUp by Registrar Corp

    How to Build a Better Training Program: Data and Insights from the Global Food Safety Training Survey

Popular Stories

half full baby bottle next to rubber duckie on white surface

Organic Infant Formulas Caused Back-to-Back Botulism Outbreaks—What Gives?

nara organics whole milk infant formula

Another Infant Botulism Outbreak Sickens Three, Nara Organics Formula Suspected Cause

smiling man with clipboard in front of bottling line at beverage manufacturing facility

The Evolving Role of the Quality Assurance Professional in Food Safety

Events

June 25, 2026

Rethinking Food Safety: Eliminating Biofilm and Building a Smarter Food Safety System

Live: June 25, 2026 at 2:00 pm EDT: Join this webinar to explore a modern approach to decontamination that goes beyond surface-level cleaning to combat biofilm and persistent pathogens.

June 30, 2026

FSMA 204 in Practice: Building a Traceability-Ready Operation

Live: June 30, 2026 at 11:00 am EDT: Attend this webinar to learn how food businesses can move from fragmented records toward a more reliable approach for recall response, FDA requests, and supply chain visibility.

July 21, 2026

Using AI Responsibly in Food Safety Management Systems

Live: July 21, 2026 at 2:00 pm EDT: This webinar will provide participants with guidance on how to effectively use generative artificial intelligence (AI) tools to develop key components of a food safety management system (FSMS).

View All

Products

Global Food Safety Microbial Interventions and Molecular Advancements

Global Food Safety Microbial Interventions and Molecular Advancements

See More Products

Related Articles

  • Food Safety Matters

    MilliporeSigma: Discussion with NIH about the Importance of Reference Materials for Dietary Supplements

    See More
  • dish of honey, honey wand, and honey pooled on table

    Italian Standards Body Offers New Standard for Method of Detecting Honey Adulteration

    See More
  • Setting the Standard with “Big Six” non-O157 STEC Reference Materials

    See More

Related Products

See More Products
  • 1119053595.jpg

    Food Safety for the 21st Century: Managing HACCP and Food Safety throughout the Global Supply Chain, 2E

  • 1119160553.jpg

    Food Safety: Innovative Analytical Tools for Safety Assessment

  • 1118396308.jpg

    High Throughput Analysis for Food Safety

See More Products

Events

View AllSubmit An Event
  • May 6, 2026

    Allergen Uncertainty: Risk Assessment, Reference Doses, and Codex Management Guidance

    On Demand: Attendees will gain insight into the importance of preparing for the industry's shift from detection-based methods to risk-based allergen management.
View AllSubmit An Event

Related Directories

  • Xcluder - Global Material Technologies

    Food processing companies and retailers around the world use Xcluder rodent and pest exclusion products to secure and protect their facilities. Xcluder’s product offering includes rodent-proof door sweeps and seals, fill fabric, and more—all made in America and safe to use around people, animals, plants, and food.
  • Gold Standard Diagnostics

    Gold Standard Diagnostics develops and markets rapid test kits and analyzers for a wide range of food contaminants including: allergens, pathogens, patulin and mycotoxins, glyphosate and pesticides, VDRs, GMOs and more. Get accurate results in minutes on-site with Gold Standard Diagnostics test kits.
×

Never miss the latest news and trends driving the food safety industry

Newsletters | Website | eMagazine

JOIN TODAY!
  • RESOURCES
    • Advertise
    • Contact Us
    • Directories
    • Store
    • Want More
  • SIGN UP TODAY
    • Create Account
    • eMagazine
    • Newsletters
    • Customer Service
    • Manage Preferences
  • SERVICES
    • Marketing Services
    • Reprints
    • Market Research
    • List Rental
    • Survey/Respondent Access
  • STAY CONNECTED
    • LinkedIn
    • Facebook
    • Instagram
    • X (Twitter)
  • PRIVACY
    • PRIVACY POLICY
    • TERMS & CONDITIONS
    • DO NOT SELL MY PERSONAL INFORMATION
    • PRIVACY REQUEST
    • ACCESSIBILITY

Copyright ©2026. All Rights Reserved BNP Media, Inc. and BNP Media II, LLC.

Design, CMS, Hosting & Web Development :: ePublishing