The World Health Organization (WHO) has officially declared popular artificial sweetener aspartame as “possibly carcinogenic to humans," although the acceptable daily intake of 40 milligrams mg/kg of body weight remains unchanged. Additionally, FDA and industry groups disagree with WHO's determination.

The Court of Justice of the European Union has ruled to annul the European Commission’s 2019 classification of titanium dioxide, which is also known as E171 and is used to add white color to foods, as a carcinogen.