During foodborne illness outbreak investigations, public health and regulatory authorities collect three types of data to determine a common food consumed by ill people: epidemiologic, traceback, and laboratory. State and local partners work with FDA to conduct traceback investigations and examine the food supply chain to determine the origin of the foods identified by the epidemiologic investigations. This article looks at the benefits of using incident command system (ICS) principles during emergency response coordination activities for foodborne illness outbreaks, with input from members of the FDA's CORE Network.