This year, Waters Corporation introduced the Waters® ACQUITY® Arc™ System--a quaternary liquid chromatograph that gives analytical laboratories running established LC methods a clear choice for replicating or improving their separations performance. With this new addition to the ACQUITY product line, the new ACQUITY Arc System is specifically engineered to respond to the needs of analytical scientists for a single LC platform that can enable them to efficiently transfer, adjust or improve their methods regardless of the LC platform on which they were developed.

To date, scientists working with established methods haven’t had an LC platform versatile enough to bridge the gap between high-performance liquid chromatography (HPLC) and ultra-performance liquid chromatography (UPLC®). With the introduction of the ACQUITY Arc System, and its enabling Arc Multi-flow path™ technology, scientists now have the ability to emulate the gradient dwell volume and mixing behavior of various LC systems. By selecting the appropriate fluidic path, the ACQUITY Arc System can easily emulate a variety of HPLC systems without altering the method’s gradient table, or provide ultra high-performance liquid chromatography (UHPLC) performance with the flip of a switch.

In addition to replicating established HPLC assays without altering the gradient table, the ACQUITY Arc System can enable improved chromatographic performance of methods by leveraging 2.5 - 2.7 micron particle column technologies, as well as support previously developed applications on 3 - 5 micron HPLC columns.

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