In a recent article published in Regulatory Toxicology and Pharmacology, a panel of experts advised against assuming that all per- and polyfluoroalkyl substances (PFAS) are equally toxic and potent. The experts’ opinions were solicited to provide insight and guidance on PFAS grouping for the purpose of assessing the substances’ risk to public health when ingested.
Scientists with expertise in PFAS or mixtures risk assessment were invited to apply to partake in a panel where they were asked about PFAS risk assessment and grouping through blind questioning. The experts were also able to review and comment on co-panelists’ responses. In total, 12 Ph.D.-holding experts from four countries were selected and provided their opinions. The panel represented academics, regulators, and consultants with expertise in PFAS chemistry, PFAS toxicology, general mixtures risk assessment, and toxicokinetics.