One of the major problems in food safety and security regulation is that many existing laws, rules, and guidelines are originated from decades-old data and methods, several of which are not even relevant to human exposure. The rationale for organizing the 1st GHI World Congress is to generate a platform to present and implement the most suitable assays for food safety and security assessment within all relevant fields—from chemistry and microbiology, to genetic toxicology and genomics—throughout entire processes, from farm to fork.